Protein name:
T-lymphocyte activation antigen CD86 ;
Alternative:
Early T-cell costimulatory molecule 1 (ETC-1) ;Activation B7-2 antigen ;
CD:
CD86 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homodimer. Interacts with MARCH8.
Function:
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation.
Subcellular Location:
Cell membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MDPRCTMGLA | ILIFVTVLLI | SDAVSVETQA | YFNGTAYLPC | PFTKAQNISL |
100:
SELVVFWQDQ | QKLVLYEHYL | GTEKLDSVNA | KYLGRTSFDR | NNWTLRLHNV |
150:
QIKDMGSYDC | FIQKKPPTGS | IILQQTLTEL | SVIANFSEPE | IKLAQNVTGN |
200:
SGINLTCTSK | QGHPKPKKMY | FLITNSTNEY | GDNMQISQDN | VTELFSISNS |
250:
LSLSFPDGVW | HMTVVCVLET | ESMKISSKPL | NFTQEFPSPQ | TYWKEITASV |
300:
TVALLLVMLL | IIVCHKKPNQ | PSRPSNTASK | LERDSNADRE | TINLKELEPQ |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rabbit
Human
ELISA Kit for Mouse T-lymphocyte activation antigen CD86
ELISA Kit for Mouse T-lymphocyte activation antigen CD86
ELISA Kit for Mouse T-lymphocyte activation antigen CD86
CLIA Kit for Mouse T-lymphocyte activation antigen CD86
CLIA Kit for Mouse T-lymphocyte activation antigen CD86
CLIA Kit for Mouse T-lymphocyte activation antigen CD86
Polyclonal Antibody for Mouse T-lymphocyte activation antigen CD86
Polyclonal Antibody for Mouse T-lymphocyte activation antigen CD86
Polyclonal Antibody for Mouse T-lymphocyte activation antigen CD86
Monoclonal Antibody for Mouse T-lymphocyte activation antigen CD86
Monoclonal Antibody for Mouse T-lymphocyte activation antigen CD86
Monoclonal Antibody for Mouse T-lymphocyte activation antigen CD86
Protein for Mouse T-lymphocyte activation antigen CD86
Protein for Mouse T-lymphocyte activation antigen CD86
Protein for Mouse T-lymphocyte activation antigen CD86
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
"Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production."
Freeman G.J.
,
Borriello F.
,
Hodes R.J.
,
Reiser H.
,
Gribben J.G.
,
Ng J.W.
,
Kim J.
,
Goldberg J.M.
,
Hathcock K.
,
Laszlo G.
,
Lombard L.A.
,
Wang S.
,
Gray G.S.
,
Nadler L.M.
,
Sharpe A.H.
J. Exp. Med.178:2185-2192(1993)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING
strain :
129 .