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Index > Protein center > Cd86(Gene name) > Mouse
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  • Cd86 (Gene name),
  • T-lymphocyte activation antigen CD86 (Protein name ),  CD86_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Cd86;
    Protein name:
    T-lymphocyte activation antigen CD86;
    Alternative:
    Early T-cell costimulatory molecule 1(ETC-1);Activation B7-2 antigen;
    CD:
    CD86;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer. Interacts with MARCH8.
    Function:
    Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    309
    Sequence:
    50:
    MDPRCTMGLA | ILIFVTVLLI | SDAVSVETQA | YFNGTAYLPC | PFTKAQNISL | 
    100:
    SELVVFWQDQ | QKLVLYEHYL | GTEKLDSVNA | KYLGRTSFDR | NNWTLRLHNV | 
    150:
    QIKDMGSYDC | FIQKKPPTGS | IILQQTLTEL | SVIANFSEPE | IKLAQNVTGN | 
    200:
    SGINLTCTSK | QGHPKPKKMY | FLITNSTNEY | GDNMQISQDN | VTELFSISNS | 
    250:
    LSLSFPDGVW | HMTVVCVLET | ESMKISSKPL | NFTQEFPSPQ | TYWKEITASV | 
    300:
    TVALLLVMLL | IIVCHKKPNQ | PSRPSNTASK | LERDSNADRE | TINLKELEPQ | 
    309:
    IASAKPNAE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    KEGG:
    String:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse T-lymphocyte activation antigen CD86
    Cat.:
    E0824m
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse T-lymphocyte activation antigen CD86
    MSDS:
    Please sign in first.
    ELISA Kit for Mouse T-lymphocyte activation antigen CD86
    Cat.:
    E0824h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse T-lymphocyte activation antigen CD86
    Cat.:
    U0824h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse T-lymphocyte activation antigen CD86
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse T-lymphocyte activation antigen CD86
    Cat.:
    U0824m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse T-lymphocyte activation antigen CD86
    Cat.:
    P0824Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse T-lymphocyte activation antigen CD86
    Polyclonal Antibody for Mouse T-lymphocyte activation antigen CD86
    Cat.:
    P0824Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse T-lymphocyte activation antigen CD86
    Monoclonal Antibody for Mouse T-lymphocyte activation antigen CD86
    Monoclonal Antibody for Mouse T-lymphocyte activation antigen CD86
    Protein for Mouse T-lymphocyte activation antigen CD86
    Protein for Mouse T-lymphocyte activation antigen CD86
    Protein for Mouse T-lymphocyte activation antigen CD86

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    Precision
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    Linearity
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    References
    1. 1.
      "Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production."
      Freeman G.J. , Borriello F. , Hodes R.J. , Reiser H. , Gribben J.G. , Ng J.W. , Kim J. , Goldberg J.M. , Hathcock K. , Laszlo G. , Lombard L.A. , Wang S. , Gray G.S. , Nadler L.M. , Sharpe A.H.
      J. Exp. Med.178:2185-2192(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Molecular cloning and expression of early T cell costimulatory molecule-1 and its characterization as B7-2 molecule."
      Chen C. , Gault A. , Shen L. , Nabavi N.
      J. Immunol.152:4929-4936(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Differential expression of alternate mB7-2 transcripts."
      Borriello F. , Oliveros J. , Freeman G.J. , Nadler L.M. , Sharpe A.H.
      J. Immunol.155:5490-5497(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING
      strain: 129.
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